LHA ID: 7Q0CR2P4G7-2
Projects: GLA - German Lymphoma Alliance
Study position:
Study type: Not specified
- MInT
- MInT
- Excellent outcome of young adults with aggressive non-Hodgkin lymphomas treated with CHOP-like regimens.
- CHOP-like chemotherapy with or without rituximab in young patients with good-prognosis diffuse large-B-cell lymphoma: 6-year results of an open-label randomised study of the MabThera International Trial (MInT) Group.
- Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma.
- Progression-free survival at 24 months (PFS24) and subsequent outcome for patients with diffuse large B-cell lymphoma (DLBCL) enrolled on randomized clinical trials.
- Parenthood in long-term survivors after CHOP with or without etoposide treatment for aggressive lymphoma.
- Standard International prognostic index remains a valid predictor of outcome for patients with aggressive CD20+ B-cell lymphoma in the rituximab era.
- Impact of rituximab and radiotherapy on outcome of patients with aggressive B-cell lymphoma and skeletal involvement.
- Long-term ovarian function in women treated with CHOP or CHOP plus etoposide for aggressive lymphoma.
- CNS International Prognostic Index: A Risk Model for CNS Relapse in Patients With Diffuse Large B-Cell Lymphoma Treated With R-CHOP.
- The role of radiotherapy and intrathecal CNS prophylaxis in extralymphatic craniofacial aggressive B-cell lymphomas.
- Suboptimal dosing of rituximab in male and female patients with DLBCL.
- CNS disease in younger patients with aggressive B-cell lymphoma: an analysis of patients treated on the Mabthera International Trial and trials of the German High-Grade Non-Hodgkin Lymphoma Study Group.
- Progression-Free Survival as a Surrogate End Point for Overall Survival in First-Line Diffuse Large B-Cell Lymphoma: An Individual Patient-Level Analysis of Multiple Randomized Trials (SEAL).
- CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large-B-cell lymphoma: a randomised controlled trial by the MabThera International Trial (MInT) Group.
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Created: 17th Apr 2019 at 12:47
Last updated: 16th May 2019 at 14:13
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B-cell lymphoma is the most frequent lymphoid neoplasia accounting for one third of all lymphomas. R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone) is the current treatment standard, leading to high cure rates especially in younger patients. Although the 3-year event-free survival is about 60% even for elderly patients between 60-80 years old, the remainder of patients eventually relapse and the majority die of their disease. The German Non-Hodgkin's Lymphoma Study ...
Programme: NHL
Public web page: https://www.dshnhl.org
Organisms: Homo sapiens
Human Diseases: non-Hodgkin lymphoma, B-cell lymphoma
Snapshots: No snapshots
Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival)
Submitter: René Hänsel
Resource type: Experimental Assay Type
Technology type: Technology Type
Investigation: MInT
Study: MInT
Human Diseases: B-cell lymphoma
Data files: MabThera International Trial Data, MabThera International Trial Data (ODM), MabThera International Trial Data (SPSS)
Snapshots: No snapshots
Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival)
Submitter: Christoph Beger
Resource type: Result Dataset of Clinical Study
Technology type: Technology Type
Investigation: MInT
Study: MInT
Human Diseases: non-Hodgkin lymphoma, B-cell lymphoma
Data files: MabThera International Trial Metadata, MabThera International Trial Metadata (ODM)
Snapshots: No snapshots
Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival)
This file contains the metadata of the MInT study formatted as CDISC ODM.
Creator: Marita Ziepert
Submitter: Christoph Beger
Data file type: ODM Data
Human Diseases: non-Hodgkin lymphoma, B-cell lymphoma
Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival)
MInT study result data as CIDISC ODM
Creator: Marita Ziepert
Submitter: Christoph Beger
Data file type: ODM Data
Human Diseases: non-Hodgkin lymphoma, B-cell lymphoma
Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival)
MInT trial data as SPSS file
Creator: Marita Ziepert
Submitter: Christoph Beger
Data file type: Clinical Data
Human Diseases: B-cell lymphoma
Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival)
Trial data of MInT
Creator: Marita Ziepert
Submitter: Christoph Beger
Data file type: Clinical Data
Human Diseases: B-cell lymphoma
Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival)
Creator: Marita Ziepert
Submitter: Christoph Beger
Data file type: Clinical Data
Human Diseases: non-Hodgkin lymphoma, B-cell lymphoma
Projects: LHA - Leipzig Health Atlas, LIFE Adult, LIFE - Leipzig Research Center for Civilization Diseases, LIFE HNC - Head and Neck Cancer Group, LIFE Heart, MMML - Molecular mechanisms in malignant lymphoma, GLA - German Lymphoma Alliance, MMML Demonstrators - Molecular Mechanisms in Malignant Lymphomas - Demonstrators of Personalized Medicine, HaematoOpt - Individualized model-based managing of the next-cycle thrombopenia of CHOEP/CHOP treated patients based on platelets dynamics during the previous cycles, e:Med, GC-HBOC - German Consortium for Hereditary Breast and Ovarian Cancer, GC-HNPCC - German Consortium for Hereditary Non-Polyposis Colorectal Cancer, MMML-MYC-SYS, NLP4CR - Natural Language Processing for Clinical Research, Genetical Statistics and Systems Biology, SepNet - German Competence Network Sepsis, LIFE Child, HNPCC-Sys - Genomic and transcriptomic heterogeneity of colorectal tumours arising in Lynch syndrome, GGN - German Glioma Network, CAPSys - Footprints of Sepsis Framed Within Community Acquired Pneumonia in the Blood Transcriptome, CapSys - Systems Medicine of Community Acquired Pneumonia, ProstataCA, HaematoSys - Systems biology of haematopoiesis and haematopoietic neoplasia, SMITH - Smart Medical Information Technology for Healthcare, Task Force COVID-19 Leipzig, NFDI4Health, POLAR - Polypharmacy, Drug Interactions, Risks, Management of health information systems, LivSys Transfer - Transfer of the LivSys in vitro system for hepatotoxicity into application, Project Test Demonstrator, Fundus photography as tool for analysis of eyes of subjects with diabetes, Clinical Trials Leipzig, NFDI4Health - TA3 Services, STOP-NUC, SCALE-TORT, EarlyAMDRate
Institutions: Institute for Medical Informatics, Statistics and Epidemiology (IMISE)

Roles: Technician
Expertise: Data Management, Data analysis, Python, Html
Projects: HaematoSys - Systems biology of haematopoiesis and haematopoietic neoplasia, GLA - German Lymphoma Alliance
Web page: Not specified